Do not stop taking letrozole unless your doctor instructs you to. If your eating problems do not improve, talk to your doctor or nurse. You may develop a mild skin rash. These drugs are often prescribed after breast cancer surgery, chemotherapy or radiation therapy to help prevent a recurrence of the disease. What happens when you stop taking Letrozole? Letrozole is a hormone therapy drug. Let your doctor or nurse know if this happens. Let your doctor know if you have pain or discomfort when urinating, if you urinate more frequently than normal, or if your urine is cloudy or foul-smelling. Talk to your specialist or advice line before you stop taking a cancer drug. Some women find that their appetite increases. Tell your doctor or nurse if this is a problem. This type of breast is called estrogen receptor-positive (ER-positive) breast cancer. Why Buy Letrozole? Hormones are substances produced naturally in the body. Withdrawal: Consult your gynecologist for a better way to discontinue your hormones. The pills are taken at the same time each day, either in the morning or at night. If this happens, your doctor may give you medicine to lower the cholesterol and fat in the blood. Three months ago I started with bone and joint pain. Letrozole is suitable for women who have been through the menopause and whose breast cancer is oestrogen receptor positive. 7. Do not stop: Letrozole ... Hi, i stopped taking femara (letrozole) two weeks ago - cold turkey and have been having a lot of headaches, dizziness, nausea, muscle and joint pains, tiredness? Yes this is a common reaction when you stop taking Femara. Some people worry about stopping their treatment, but there’s evidence that exemestane continues to reduce the risk of breast cancer coming back for many years after you stop taking it. Research has shown that about 25% of women who are prescribed hormonal therapy to reduce the risk of recurrence after surgery either don’t start taking the medicine or stop taking it early, in many cases because of side effects. If you have any problems with the way your liver works, or any problems with the way your kidneys work. 4. Except when it is almost time for your next dose, do not take a double dose. They should be stored away from heat and direct sunlight. Talk to your doctor if side effects from Arimidex are persisting despite stopping it. Do not start, stop, or change the dose of any drug without checking with your doctor. Letrozole belongs to a group of drugs called aromatase inhibitors. If hot flashes are troublesome: • Try taking your letrozole at bedtime. It blocks this process and reduces the amount of estrogen in the body. I know it's scary but I had an allergic reaction to letrozole and had to stop taking all my medication including my in gales and lanzaporole and then slowly introduced them back but not the letrozole I have now been put on exemestane and yes still have joint pain but if it's to bad I take paracetamol. Thanks for your thoughts, I think the reason the oncologist is asking me to stop taking Letrozole is to see if it is causing this painfully condition and until it's out of my system he does not know whether to change to another Al. Registered Office: Fifth Floor, Ibex House, 42-47 Minories, London EC3N 1DY. #2 is possibly just the inability to bounce … However, they may be more problematic for some women. If you’re having chemotherapy or radiotherapy, your specialist will tell you when it’s best to start letrozole. This includes medications that can be purchased in a store or pharmacy. ohilly. You should not stop taking Letrozole without discussing with your physician. Keep them safe and out of the reach of children. #1 is a problem with my hands, unable to make fists or grip a knife to cut meat, hands feeling swollen every morning. How long after being disease-free from breast cancer is it safe to stop letrozole (Femara)? Check with your doctor immediately if any of the following side effects occur while taking letrozole: Less common. It is also used to treat early breast cancer in women who have experienced menopause and who have already been treated with a medication called tamoxifen (Nolvadex) for 5 years. "If the side effects from letrozole are intolerable, benefits are maintained by switching to tamoxifen rather that stopping hormonal therapy altogether." This is why, this product can be stopped abruptly. This treatment can cause vaginal changes. 8. You will normally have a bone density scan to check on the healthiness of your bones before and during the treatment. Talk to your specialist, pharmacist or GP about any complementary therapies, herbal remedies or supplements you want to use before you start using them. Sometimes it may be possible to change to another hormone drug. Do not take other drugs containing oestrogen, such as hormone replacement therapy (HRT), while you’re taking letrozole as this may interfere with its effectiveness. It is very important that you contact your doctor immediately if you develop a sever rash. Tell your doctor if you notice this or any other type of swelling. Tell your doctor if you are taking any other medication. Always inform your doctor or nurse of the side effects you experience. Some people worry about stopping their treatment, but there’s evidence that letrozole continues to reduce the risk of breast cancer coming back for many years after you stop taking it. Talk to your nurse or doctor if you experience these changes so that they can give you support and. Letrozole is a drug called an aromatase inhibitor. Both tamoxifen and aromatase inhibitors can cause side effects. Let your health professionals know if you have any of these symptoms. However, some side effects, such as high cholesterol, lymphedema, osteoporosis, and vaginal dryness may persist despite discontinuation of Arimidex. Eating healthy meals and becoming more physically active can help you maintain a healthy weight. This medicine may make you dizzy, drowsy, or tired than they are normally. They can normally suggest ways to improve the side effects. 1. It should go away when the drug is out of your system which shouldn't take longer than 4 days to a week. • If night sweats interfere with sleep, try taking your letrozole in the morning. If you miss a dose, you don’t need to take an extra dose the next day. These act as chemical messengers and help control the activity of cells and organs. Less pain in the knees but still getting better gradually. Sometimes it may … How does letrozole work? Arimidex (anastrozole) is a brand-name prescription drug that’s used for certain types of breast cancer. If you have any questions about this, talk to your doctor. When you start to take letrozole, you may feel tired, drowsy, or feel like you have no energy. Low doses of certain antidepressants can help reduce hot flashes. Letrozole can also be used to treat breast cancer that has come back (recurrence). There are a number of other brands of letrozole, all of which contain the same dose of the drug. It the side effects are very bothersome and are unmanageable, your oncologist may suggest you start on a different hormone therapy. Letrozole can also cause indigestion or abdominal pain. After menopause, estrogen is no longer made in the ovaries. Hormone therapy is a very common treatment for secondary breast cancer and many people take it for a long time. If you’re taking letrozole to treat breast cancer that has come back or spread to another part of the body, you’ll usually take it for as long as it’s keeping the cancer under control. If you are taking other drugs, you may have certain side effects that are not listed here. If you're taking adjuvant hormonal therapy medicine now, stick with it as prescribed. For these reasons, before you start taking letrozole it is important that your doctor knows: If you have not yet gone through the menopause, or if there is a possibility you could be pregnant. I hope this … What are some things I need to know or do while I take Letrozole? If you’re taking any other prescribed or over-the-counter medicines, check with your treatment team or pharmacist if you can take these with letrozole. Doctors sometimes prescribe it before or after another type of hormone therapy. However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back. Letrozole may cause dizziness. One more time/what happens when you stop AIs. Men with breast cancer may be given letrozole, although another drug called tamoxifen is more commonly used. Most side effects settle down a few months after taking letrozole or can be controlled or managed. Drink lots of fluids if you think you may have an infection. Learn about side effects, warnings, dosage, and more. Letrozole is also used to control breast cancer that has spread to other parts of the body (secondary breast cancer). There is hope after this med! Do not stop taking letrozole unless your doctor instructs you to. How long will I have to take it? The study also looked at how stopping hormonal therapy affected the women's risk of dying. Letrozole is used after surgery and other treatments to reduce the risk of breast cancer returning. Some people worry about stopping their treatment, but there’s evidence that letrozole continues to reduce the risk of breast cancer coming back for many years after you stop taking it. You should take the right dose, not more or less. Tamoxifen may cause hot flashes. Letrozole works by reducing the amount of oestrogen made in the body. Along with its needed effects, letrozole may cause some unwanted effects. Hormone therapies interfere with the way hormones are made or formed in the body. If you are at risk of developing osteoporosis, your doctor may prescribe drugs called bisphosphonate to protect your bones. What is letrozole? I stopped taking it a month ago cause My hips and shoulders felt like they were coming out my sockets. Letrozole is a drug used to treat breast cancer in women who have gone through the menopause. Casper says that about 1 percent of people who take letrozole get leg cramps and headaches, but the good news is that these symptoms go away once you stop taking the pills. In the study, 13% of women stopped taking the drugs due to side effects such as joint and muscle pain. If you’re thinking about stopping taking letrozole for any reason, talk to your specialist first. Letrozole can interact with other drugs. You may experience some of the side effects mentioned here, though it is rare for a patient to have all of them. Hot flashes and sweating can subside after the first few months. Try to pace yourself until this improves. Letrozole is taken as a tablet once a day, with or without food. Occasionally, letrozole may be used as the first treatment for breast cancer, for example when surgery isn’t appropriate or needs to be delayed. The amount of Letrozole that you will receive depends on many factors, including your general health or other health problems, and the type of cancer or condition being treated. HOT FLASHES AND SWEATING. 6. Taking letrozole with other drugs. You may also hear it called Femara, which is its best-known brand name. It is very important that you do not stop taking letrozole without telling your doctor, as this may affect the success of the treatment. In this section, you can read about why it's so important to stick to your treatment plan and ways to handle possible difficulties in following radiation, chemotherapy, and hormonal therapy regimens. Tell your doctor if this does not get better. If your cancer is hormone receptor negative, then letrozole will not be of any benefit. I finished taking 5 years of first Tamoxifen then Letrozole, 2.5 years each. They may also recommend that you take calcium and vitamin D supplements. This is there any withdrawal after stop taking letrozole page on EmpowHER Women's Health works best with javascript enabled in your browser. These drugs, which include Arimidex (anastrozole), Aromasin (exemestane), and Femara (letrozole), are usually given to postmenopausal women. Tell your doctor if your hot flashes become bothersome. To hear from us, enter your email address below. Here, we explain the most common side effects of letrozole. The half life of the drug is 2 days so it should be out of your system within 4 days. You won’t need to stop taking it gradually. Healthy eating and staying physically active will help if you have worries about your weight. You can buy these from a chemist, or your doctor can prescribe them. Letrozole is also used in women who have experienced menopause as a first treatment of breast … Your ankles and feel may swell up because of the build-up of fluid. Letrozole can harm an unborn baby. Always take the pills exactly as your nurse or pharmacist has told you. Let your doctor or nurse know if this happens. Explain that you are taking hormone therapy and that no one should start or stop it without taking to your cancer specialist in the first place. These are common and tend to be mild, though they can vary. Although not all of these side effects may occur, if they do occur they may need medical attention. We have … Instead it's made in the fatty tissues of the body. You may gain weight when taking hormone therapy. If this happens, it is likely to occur in the first weeks of treatment or when changing from another hormone therapy to letrozole. This happens when an enzyme called aromatase changes other hormones into estrogen. I completed the full five years as prescribed. 3. Who it’s suitable for Some people start taking letrozole after a few years of taking the hormone therapy drug tamoxifen. Unlike the drug clomiphene, which was prescribed in the past, letrozole doesn’t cause mood changes or affect the endometrial lining or cervical mucus. If your vaginal bleeding continues for more than a few days, tell your doctor or nurse. This may increase the risk of bone fractures. I had bad joint pain in my knees for the full time and hot flashes as well as some foggy mental functioning. Use effective birth control if you are not past menopause. Hospital Universitario Fundación Jiménez Díaz, Strategic plan of the Oncohealth Institute. Sometimes letrozole is given alongside a drug called goserelin (Zoladex) to women who haven’t yet been through the menopause. In rare cases, women may have vaginal bleeding. These are common and tend to be mild, though they can vary. This is normally mild. However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back. Less common but more severe side effects of aromatase inhibitors are heart problems, osteoporosis, and broken bones. Dr. Edward Smith answered. 5. If you have any worries or questions about taking or stopping letrozole, you can call us free on 0808 800 6000 to talk through your concerns. Dress in layers so you can remove clothing if you need to. Posts: 446 Joined: Jan 2008 Apr 10, 2009 - 5:23 pm. No one responded to my post about this, so I'll try again: I've only been taking Femara, but I'm already wondering: so what happens in 5 or 10 years (new research shows we might have to be on this stuff longer) when we stop taking our aromatase inhibitors? If letrozole stops working, your specialist may prescribe another hormone drug. Letrozole is used treat early breast cancer in women who have experienced menopause (change of life; end of monthly menstrual periods) and who have had other treatments, such as radiation or surgery to remove the tumor. If you have a loss of bone density, or 'brittle bones' - a condition known as osteoporosis. Find out more about the side effects of letrozole. Always tell your doctor or nurse about any change to your eyesight. Taking letrozole for a number of years increases the risk of bone thinning (osteoporosis). You may have pain or stiffness in the joints, or sometimes in your muscles. However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back. Nausea is usually mild, but tell your doctor or nurse if this happens. I hope this helps. Aromatase inhibitors may cause muscle and joint aches and pains. • Some people find it helpful by avoiding alcohol, spicy food, caffeine intake (coffee, tea, colas, chocolate). Your hair will thicken after the treatment ends. These include complementary therapies and herbal remedies. Letrozole is taken once a day in tablet form. It’s best to take it at the same time every day. Natural fabrics such as cotton may be most comfortable. They can prescribe drugs to help control them and can also give you advice on managing side effects. Get a new prescription before the one you have runs out, and keep track of holidays, when pharmacies may be closed. Bone fracture; breast pain; chest pain A study reports on the results of several different studies looking at how often side effects made women stop taking hormonal therapy. Posted: December 2, 2011; If you would like to reproduce some or all of this content, see Reuse of NCI Information for guidance about copyright and permissions. Taking short walks regularly will help you feel less tired. Your treatment team will tell you when to stop taking letrozole. Side effects of letrozole I have another appt booked at the oncology clinic in early December so I will talk further about it with whomever I see at that time. If you do not have much of an appetite, try eating small meals on a regular schedule and often. 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